DR. PHILIP WATKINS: So, technically, from a herbal medicine standpoint, I guess, you’ve actually gone too far, and you’ve ingested, if you like, too much THC. Because technically you should have a relaxed feeling. You should feel the benefits but you shouldn’t get any further than that.
CHRISTEL: I see.
DR. PHILIP WATKINS: So, to your point though, yeah hemp shouldn’t get you high. It’s non-psychoactive and it works with the receptors that are all over the body, and this is why the cannabinoid system is of such interest, because there are receptors for the cannabinoids and CBD in the lungs, the heart, the digestion, the peripheries – so your arms and legs, pretty much everywhere.
CHRISTEL: So, what is this system, the internal system that you speak of, what is it in the body? What is it referring to? Nerve endings, or blood, or what is it?
DR. PHILIP WATKINS: Yeah, so the big thing about it more than anything is that it’s primarily driven towards actually being around to help the different systems and the different organs of the body. So, the endocannabinoid system itself refers to the collection of the receptors. So, there are CB1 receptors in the brain and the spinal cord. Then there are CB2 receptors in the other periphery areas, so the lungs, and the heart, and the immune cells, and the pancreas and that type of thing. This is where it becomes quite exciting, because we understand that CBD is what we call a polytrophic, so that’s just a fancy name for it has more than one effect. Vitamin D is also polytrophic in that it has more than one effect on the body. So, the reason why this system is actually being researched a lot is because it can have quite a whole-body effect on everyone really, because we all have this endocannabinoid system. So, it’s really, really exciting.
CHRISTEL: That is wild.
DR. PHILIP WATKINS: It is crazy isn’t it, that everyone’s got it? You know, and you can – yeah.
CHRISTEL: And yet, you know, I mean, I don’t even know how to refer to it as a substance, as an herb or a medicine, or however you want to refer to it – it’s been so stigmatised.
DR. PHILIP WATKINS: It is, yeah, and that’s changing.
CHRISTEL: Yeah, it is.
DR. PHILIP WATKINS: It needs to change as well, and I think, just broadening that, you know, you’ve got other forms of medicine that are also having their stigma changed. I’ve been following Rick Doblin who has created an association called MAPS, which is – the name’s quite strange – in the Multidisciplinary Association for Psychedelic Studies. But he created a strategy after the Vietnam War to use MDMA for post-traumatic stress syndrome, stress disorder.
And it’s taken fifty years now and that is now, as of last year, been funded to actually help veterans with PTSD. So, there’s a really big change in the air in relation to things that we have originally – you know, without being too hyperbolic about it, originally demonised or had a negative relationship with, and now seeing that they can actually help us.
CHRISTEL: Yes, I mean, you know, to compare it to something like alcohol, which is perfectly legal and yet perfectly abused at the same time.
DR. PHILIP WATKINS: Sure, sure. So, I think this is where we need to find a happy balance between the educational side of it. Obviously, from a therapeutic element, we need to really, kind of, help people understand cannabis, and I think, moving away from – maybe educating people a little bit more about how marijuana was named, for example.
CHRISTEL: Yes.
DR. PHILIP WATKINS: I think the other side of this, though, is that we often think about cannabis for its acute elements as well, and I think one of my personal interests in relation to CBD is actually more related back to what’s called the glymphatic system in the brain. Now, tell me if I’m talking too much.
CHRISTEL: No, no.
DR. PHILIP WATKINS: I get excited about this. One of the reasons why you need to go to sleep, alright, is that your brain-
CHRISTEL: Because I’m tired.
DR. PHILIP WATKINS: No, this is, because you’re exhausted, yeah. It is because your brain actually needs to clean house. The glymphatic system is kind of a collection of different kind of vessels and transport systems that actually clean the waste products out of your brain, but also help to potentially transport neurotransmitters like serotonin and the chemicals that make you feel good. Also, other things that are really important like glucose. This process of somewhat brain detoxing while you’re sleeping is governed by a chemical called an astrocyte. Now, one of the cool things about CBD is that CBD actually is now considered to increase the levels of astrocytes in the brain, so that when you go to sleep you have got enough stimulus for the brain to detoxify itself. Now, when it comes to aging, one of the reasons why this glymphatic system is quite interesting to people is because, as you age, your glymphatic activity goes down, it actually reduces. This is where we start to see that the brain is unable to somewhat clean itself and this may be potentially why we’re seeing a higher incidence of things like Alzheimer’s and dementia, and some of these other brain degenerative diseases.
CHRISTEL: Wow.
DR. PHILIP WATKINS: Because it just can’t clean itself.
CHRISTEL: Dirty mind.
DR. PHILIP WATKINS: Indeed, yeah I didn’t think that, but you’re right on. It’s literally like that, though, right? And you talk about clean eating as another side of that. But then, you know, having this consistent astrocyte level, it means that we may actually be able to find a way through long-term administration of something like CBD. And, you know, hemp seeds – there are new ways of coming out with this. They may actually really protect our brains for a lot longer. So, whilst we kind of consider anti-inflammation, there’s some really great research in psoriasis for skin from the anti-inflammatory nature of CBD, osteoporosis – there are a lot of things that people don’t necessarily know about. But, as I said for me personally, I think we’re all worried about both for ourselves, our parents and our grandparents, I guess having a cognitive decline of sorts and we may, through the attenuation of this system or managing the endocannabinoid system with CBD, we may have found a potential way to, kind of, somewhat protect or at least stem the decline. So, there are longer term benefits coming out of the research that might be really super, super beneficial for everyone.
CHRISTEL: So, let’s talk about how you actually take CBD. I guess, how is it best effective to stimulate or speak to your endo-say it again?
DR. PHILIP WATKINS: Endocannabinoid system.
CHRISTEL: Endocannabinoid system. How best to do that?
DR. PHILIP WATKINS: Great question. So, it really just depends on what you want. I think the CBD oil is one of the things that, I guess, originally came onto the market. I’ve used it topically for skin as well, so there are measures that you can take in order to help people.
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As I said, my, you know, this has really only been available to me over the last two years or so, or, say, a year. So, my clinical kind of outcomes are still coming around, but, topically, you can, I have seen some great results. So, I think the research is moving towards what’s called an oral buccal spray. So, actually spraying it on the inside of your cheek, which, somewhat then kind of dodges the digestion.
CHRISTEL: Straight to the bloodstream, I guess.
DR. PHILIP WATKINS: Right on, yeah. So, in that, if you’re using it as a medicine, for example, so Sativex or some of the other FDA-approved or NHS-approved forms of medical cannabis, they’re generally in a spray. As I said, if you’re looking to use it as somewhat of a supplement, then the oil or, you know, less intense version of the spray is probably a good one. For the skin, definitely try it topically.
CHRISTEL: Right, right, right. So, in terms of a sort of, I guess, governing body in Hong Kong, do we have one for this sort of stuff?
DR. PHILIP WATKINS: The Hong Kong Health Department is the primary one. Through the small amount of work that I’ve done with them, everyone’s still working it out. One of the reasons why this is the case is because the research is still very preliminary. So, there are certain – as I said, the rule is that if you have a lab go through your CBD offering, and it has 0% THC, at this point, in my understanding, at the time of this recording, it’s considered to be just fine.
CHRISTEL: Amazing. So, if I may, have you yourself, do you have any anecdotal, sort of any stories or anything, about your own personal experience of the benefits of this?
DR. PHILIP WATKINS: Sure. So, I think I can certainly speak to it from anecdotally on what I’ve used in the clinic. I think one of the cool things that, I think, I like to see is the fact that, I guess, when I treat someone’s digestion, for example, the way we perceive our environment in relation to, you know, threats and things like that are naturally going to tell our brain that it’s not safe to eat. That information then gets fed through the body and, you know, oftentimes the digestion will, kind of, receive that message and say okay well I’m going to turn myself off while you go and deal with that threat, and then we can eat when we feel safe.
Now, for a lot of people, the perception of that threat is constant, and, you know, work, email, you know, everything – 2020. So, for me, using CBD to help people, kind of, take the edge off that threat. And notice I’m not using the word stress, because I think in 2020 we can just all just say that that’s a pretty universal characteristic for all of us. But using CBD actually as part of a protocol to help someone in the broader sense has been really, really interesting to see, because that’s where I’ve gotten the best results is actually by understanding that we’re not just headless horsemen and women, and that if we come in with particular conditions such as the digestion – you know, your average kind of bloating or abdominal discomfort or things like that, that utilising something like CBD both to work with the whole system but also to work with the brain so that you can essentially give someone the mental space to, maybe, do what they need to do for themselves, you know, maybe a little bit of exercise, or change their eating behaviours – that’s been probably the most rewarding part of using CBD with my stuff.
CHRISTEL: Interesting, because I guess, you know when you say when the body or the person senses a threat and then that’s your body telling you it’s not safe to eat –
DR. PHILIP WATKINS: Mm-hmm.
CHRISTEL: My body tells me it’s way too safe to eat a lot.
DR. PHILIP WATKINS: Yes, indeed. Look, this is, I think, so, this is the interesting thing, right? Even though you eat when you feel like it’s not safe, okay, which is fine, your body, when it comes to your digestion, won’t get –
CHRISTEL: Yes. So, I guess what I’m getting at is that perhaps something like CBD can actually put us in better touch with our bodies, because we’re so out of touch with what we need, right?
CBD can actually put us in better touch with our bodies